Posh head to the Stadium of Light to face Premier League side Sunderland on Tuesday evening (7.45pm).
Peterborough United travel to Premier League side Sunderland in the third round of the Capital One Cup on Tuesday evening (7.45pm).
Sunderland parted company with manager Paulo Di Canio on Sunday evening so club legend Kevin Ball taking charge of this cup-tie.
Mark Little and Nathaniel Knight-Percival will be missing as they serve the first of a three-match ban. The club will not be appealing the dismissals.
Ferguson said: 'We’ve looked at the red cards several times, but we see no point in appealing so others will get the chance. Gaby and Kgosi will hopefully take the opportunity to impress, while I’m pleased to be able to get Brisley back into the squad.
'The lads were fantastic on Saturday, but they were quiet this morning (September 23), probably because of fatigue. They trained well and they looked sharp by the end of the session so I don’t think tiredness will be a factor tomorrow.
'It’s a big game for us and it’s one we want to win. There’s no point in even travelling up there if we didn’t think like that.
'It’s a brilliant stadium to play in and there should be a decent crowd. We’ve not beaten a Premier League team in my time at the club so I’d love that to change,' Ferguson said.
The Posh boss expressed his surprise at the departure of Di Canio, but insisted it was about his team's performance. Daniel Kearns misses the trip due to injury, but he should be fit for the trip to Rotherham United on Saturday.
Tyrone Barnett is at 9/1 for 1st scorer V’s Sunderland with @betbright. (twitter) www.betbright.com/theposh
Posh had sold close to 400 tickets for the game in advance with supporters able to pay on the turnstiles.